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regumate for mares

Milk: Not permitted for use in lactating animals producing milk for human consumption. 15-day treatment regimen allows performance horse to compete at their best. Talk to your veterinarian about proper use and safe handling of Regu-Mate®. Administer solution directly on the base of the mare's tongue or on the mare's usual grain ration. Remove cover from bottle dispensing tip and connect luer lock syringe (without needle). Copyright © 1995-2020 Intervet Inc., doing business as Merck Animal Health, a subsidiary of Merck & Co., Inc. All rights reserved. It is the only such medication proven to have progesterone-type biologic activity in the horse. Regumate is one of a handful of products used to regulate the period cycles of fillies and mares and those cycles are most disruptive in the spring. REGUMATE IN STALLIONS – Effects on Reproductive Performance Patrick M. McCue DVM, PhD, Diplomate American College of Theriogenologists Regumate® or altrenogest is a synthetic progestin approved for suppression of estrus in mares. Dolorex® (butorphanol tartrate injection), Protazil® (1.56% diclazuril) Antiprotozoal Pellets, Trust genuine REGU-MATE® (altrenogest) Solution 0.22% for proven palatability, bioavailability and efficacy in every dose, The only FDA-approved altrenogest with more than 50 million doses sold, Delivers safe, predictable control over a mare’s reproductive cycle and reduces undesirable mood and behavioral changes, 15-day treatment regimen lets performance mares compete at their best, Strategic use helps accommodate mare’s performance schedule, Easy-to-administer with REGU-MATE® dosing device. In mares with significant follicular activity during the transitional period between seasonal anoestrus and the breeding season (follicles of at least 20-25 mm present at the beginning of treatment): Suppression/prevention of oestrus (usually after 1 to 3 days of treatment) during the prolonged oestrus periods occurring dur ing this period. (Note: Do not remove syringe while bottle is inverted as spillage may result.) Replace cover on bottle dispensing tip to prevent leakage. The Regumate Dosing Device is easy to dismantle for cleaning and re-lubrication. For mares that aren't cycling normally, putting them on regumate for 14 days and then taking them off can help them come into a normal heat. The good news is that Regumate, one of the more popular equine progesterone treatments for mares on the market, is not the only option you may have to regulate her cycles. Excessive use of a syringe may cause the syringe to stick; therefore, replace syringe as necessary. The day of the major event or stakes arrives and the prize mare is ready to compete. I am not at all a fan of regumate. It contains altrenogest, a short-acting synthetic steroidal progestogen. It can be given directly by mouth or on your mare's grain ration. Mares have been given Regumate for up to 60 days and then bred with no adverse effect on fertility. Helps balance mood and focus for more consistent training and performance. Regumate and Positude are different. This may result in reduced functionality and affect the graphical presentation of this site.However, all content will still be available. Suppression of estrus will also facilitate management of prolonged estrus conditions. Learn more about REGU-MATE, the original altrenogest solution for horses. Available in 1000 mL bottles along with a dispensin cap. Suppression of estrus allows for a predictable occurrence of estrus following drug withdrawal in mares with ovarian follicles 20 mm or greater. Keep detailed and secure records of all mares that are treated with Regumate Equine for justifiable veterinary reasons and evidence to confirm that they were believed to be permanently retired from racing, at the time of treatment. The Ergonomic design gives maximum user comfort and stylish looks. Messing withe the body in that manner just isn't something that should be … Natural or synthetic gestagen therapy may exacerbate existing low-grade or ‘smoldering’ uterine inflammation into a fulminating uterine infection in some instances.PrecautionsVarious synthetic progestins, including altrenogest, when administered to rats during the embryogenic stage of pregnancy at doses manyfold greater than the recommended equine dose caused fetal anomalies, specifically masculinization of the female genitalia.WarningREGU-MATE (altrenogest) Solution 0.22% is readily absorbed by the skin. It may be used to suppress and prevent the signs of oestrus in mares, which may be particularly useful early in the breeding season. Regumate Porcine uses ORAL PROGESTIN SOLUTION 0.22% (2.2 mg/mL) FOR USE IN ANIMALS ONLY For suppression of estrus in mares. Pregnant women or women who suspect they are pregnant should not handle Regu-Mate… Skin contact must be avoided as Regu-Mate® (altrenogest) Solution 0.22% is readily absorbed through unbroken skin. Lost over $300 including cost of gun. Suppression of estrus allows for a predictable occurrence of estrus following drug withdrawal in mares with ovarian follicles 20 mm or greater. When you stop, she'll probably come into heat within five to 10 days. Regumate Equine 0.22% Oral Solution. Mares have been given Regumate for up to 60 days and then bred with no adverse effect on fertility. Regu-Mate Solution Indicated to suppress estrus in mares. Page 1 of 1 Start over Page 1 of 1 . Pregnant women or women who suspect they are pregnant should not handle Regu-Mate® (altrenogest) Solution 0.22%. Most people find that Positude is so effective in addressing their mare’s behavior that they do not need Regumate, but it is ok to use both. Regumate®is the hormone most commonly prescribed for suppression of estrus in mares. Draw out appropriate volume of REGU-MATE solution. Positude helps address the behavioral side effects associated with the estrus cycle. REGU-MATE (altrenogest) Solution 0.22% is indicated to suppress estrus in mares. Regumate 1 contains the drug Altrenogest, a synthetic progestagen, and is labeled for use in mares to suppress estrus (heat) display. Copyright © 2020 Intervet Inc., a subsidiary of Merck & Co., All Rights Reserved. After one week she get swelling face, and leaking eye. Keep your clinic up-to-date on the Merck Animal Health line of equine products. Regu-Mate® (altrenogest) Solution 0.22% is indicated to suppress estrus in mares. Altren® is manufactured in Minnesota in a GMP facility registered with FDA. Regu-Mate(altrenogest) is a liquid oral medication that provides a synthetic source of progesterone. Suppression of estrus allows for a predictable occurrence of estrus following drug withdrawal. And it improves most mares on the racetrack who are on it. Customers also viewed these products. Each ml contains 2.2mg altrenogest. Regumate is the trade name for a synthetic hormone called altrenogest. Suppression of estrus allows for a predictable occurrence of estrus following drug withdrawal. Imagine going through your whole month's hormonal changes in a matter of hours. Protective gloves must be worn by all persons handling this product. Preventing Estrus In Performance Mares. Draw out appropriate volume of Regu-Mate® solution. DosageWhile wearing protective gloves, remove shipping cap and seal; replace with enclosed plastic dispensing cap. Talk to your veterinarian about proper use and safe handling of REGU-MATE® (altrenogest) Solution 0.22%. Excessive use of a syringe may cause the syringe to stick; therefore, replace syringe as necessary.ContraindicationsREGU-MATE (altrenogest) Solution 0.22% is contraindicated for use in mares having a previous or current history of uterine inflammation (i.e., acute, subacute, or chronic endometritis). Regumate Equine is a hormonal treatment for mares containing the synthetic progestagen altrenogest. Regu-Mate® suppresses estrus in 95 percent of mares after three days of treatment.1 When treatment is discontinued, mares return to estrus within four to five days. Regumate is designed to prevent a mare from cycling, but Positude is not. Suppression of estrus allows for a predictable occurrence of estrus following drug withdrawal in mares with ovarian follicles 20 mm or greater. Trust the original altrenogest solution for horses. Pregnant women or women who suspect they are pregnant should not handle REGU-MATE® (altrenogest) Solution 0.22%. Clinical uses of Regumate include management of the transition period, suppression of heat in performance mares and maintenance of pregnancy in problem mares. When treatment is discontinued, mares exhibiting regular estrous cycles return to estrus within 4 to 5 days following treatment and continue to cycle normally. CONTRAINDICATIONS Regu-Mate® (altrenogest) Solution 0.22% is contraindicated for use in mares having a previous or current history of uterine inflammation (i.e., acute, subacute, or chronic endometritis). It makes measuring the dose as easy as turning a dial, and limits skin exposure to the drug. Regumate® is a man made progestane, altrenogest, that has strong progesterone properties and can be placed in the feed. While wearing protective gloves, remove shipping cap and seal; replace with enclosed plastic dispensing cap. For owners or exhibitors of mares, you will be limited to the use of Regumate to control estrous. Regu-Mate ® (altrenogest) Solution 0.22% may be administered early in the transition period to suppress estrus in mares with inactive ovaries to aid in the management of these mares or to mares later in the transition period with active ovaries to prepare and schedule the mare for breeding. Possible Side Effects When used as directed on the label, Regu-Mate is usually tolerated well by horses. Regu-Mate Suppression of estrus allows for a predictable occurrence of estrus following drug withdrawal. Each ml of Regu-Mate Solution contains 2.2 mg altrenogest oral progestin. Suppression of estrus allows for a predictable occurrence of estrus following drug withdrawal in mares with ovarian follicles 20 mm or greater. Regumate and Positude are different. To understand fully how these drugs work, first, let’s briefly review the science behind mares’ cycles—when they happen and why. This facilitates the attainment of regular cyclicity during the transition from winter anestrus to the physiological breeding season. This facilitates the attainment of regular cyclicity during the transition from winter anestrus to the physiological breeding season. Simply apply the Regu-Mate solution at either the base of the mare's tongue or directly on her grain. In recent years, some have presented it as having an almost legendary ability to support pregnancies in mares that otherwise appear unable to … Regumate may be used to manage the behaviour of mares that exhibit prolonged oestrus cycles, supressing oestrus in mares that display undesirable behavioural changes. Always wear protective gloves when administering Regu-Mate®. Suppression of estrus will also facilitate management of prolonged estrus conditions. Another fact: At present, USEF is considering a future ban on the use of Depo- Provera in all horses. Always wear protective gloves when administering REGU-MATE® (altrenogest) Solution 0.22%. Toggle navigation 76. Regu-Mate is for administration orally on back of mare’s tongue or applied to usual grain ration. The good news is that Regumate, one of the more popular equine progesterone treatments for mares on the market, is not the only option you may have to regulate her cycles. The same formulation and active ingredient a Regu-Mate®. It is also commonly used to help maintain pregnancy in mares determined to be at risk of pregnancy loss. Almostafarm - 2017-08-23 8:40 PM Are there any good alternatives to regumate that can be administered? Progesterone for 14 days (Regumate or IM injection of progesterone) Progesterone (or P+E) for 7 days or long acting progesterone (1 injection), PGF2a on day 7 ; PGF2a: single injection (mares are responsive only when there is a functioning CL present: day 5-12 of cycle, 80% of mares respond) REGU-MATE® (altrenogest) Solution 0.22% is contraindicated for use in mares having a previous or current history of uterine inflammation. Regumate® is the trade name for a synthetic hormone called altrenogest. Regu-Mate effectively suppresses oestrus in 95 percent of mares after 3 days of treatment through alleviating moodiness … It is supplied as a liquid to be given directly into the mouth, or added to a small amount of food. Regu-Mate (altrenogest) Oral Progestin is indicated to suppress estrus in mares. Regu-Mate® Solution 0.22%, DIN 00641987, is an oral progestin used to suppress estrus or as an adjunct to help maintain pregnancy in some mares. I stop giving her regumate and after 3 more days she has problem walking she has problem to urinate her eye’s do not react on light, she looks like get some neurological problem. Use to schedule estrus in mares and breeding in mares to maximize breeding efficiency. Restrict access to and administration of Regumate Equine to specifically selected and trained staff. Helps reduce sensitivity to being groomed or tacked-up. Oral altrenogest is no longer under patent, and is … One is designed to last 7- 10 days and the other is a 30 day treatment. It may be used to suppress and prevent the signs of oestrus in mares, which may be particularly useful early in the breeding season. Regumate® is occasionally administered off-label to stallions in an attempt to suppress undesirable male behavioral characteristics We just started my mare on 3 ml of im altrenogest that she gets once a week for four weeks and then possibly reduced down to every three weeks - I THINK this is the p+, but I'm wondering how such a low dose works and how it is different from the p4 ( which I know nothing about) and the boirelease. Which is when Peters will bring his superstar mares ARCADIA QUEEN and ENTICING STAR to the east coast. For mares that have low progesterone levels after they've conceived, it can help them keep their hormone levels high enough to maintain a pregnancy until their body starts manufacturing on their own. Historically only available as Regumate, this is the only FDA-approved treatment for estrus suppression in mares. “If we can assume for a moment that it is, then we are clearly making an exception to say that mare behavior is so atrocious, or can be that we’re going to make an exception for mares, but we’re not going to make an exception for stallions. The Regu-mate Dosing Device helps to make dosing easy. (Note: Do not remove syringe while bottle is inverted as spillage may result.) Regu-Mate ® (altrenogest) Solution 0.22% is indicated to suppress estrus in mares. Administer orally with dose syringe or by placing directly on feed. She had been having intermittent behavior and stiffness issues that after seeing several vets could not be attributed to any lameness issues. How soon normal oestrus cycles will return post-treatment will again depend on the ovarian activity of the individual mare … Each ml contains 2.2mg altrenogest. Skin contact must be avoided; protective gloves must be worn when handling this product. It may be used to suppress and prevent the signs of oestrus in mares, which may be particularly useful early in the breeding season. Regu-Mate (altrenogest) Solution 0.22% is indicated to suppress estrus (period of the reproductive cycle when the mare ovulates and, if bred, is likely to conceive) in mares. It is meant to be used for the suppression of estrus in mares. The oral synthetic progestin altrenogest (Regumate Equine, MSD Animal Health) is the only treatment licensed for the suppression of oestrus in mares in the UK. If the owner does not want to give the oral altrenogest daily, there are injectable altrenogest products that are compounded. Helps settle squealing and excess flirting. Natural or synthetic gestagen therapy may exacerbate existing low-grade or "smoldering" uterine inflammation into a fulminating uterine infection in some instances. Regumate Equine is a hormonal treatment for mares. Regumate® or altrenogest is a synthetic progestin approved for suppression of estrus in mares. The proper use of progesterone and Regumate® requires understanding the hormones actions. Equine veterinarians have several ways to prevent estrous behavior. Hi I have a mare who can be extremly unpredictable (when ridden) and very marish (pulling faces, threateneing to kick etc) when coming into/ having a season and last year I put her on regumate after speaking to the vet and after trying herbal feed supplements (and after having a physio and dentist check her just incase there was anything underlying there etc). Storage. Oral altrenogest is no longer under patent, and is … It has happened to many horse owners. Clinical uses of Regumate® include management of the transition period, suppression of heat in performance mares, and maintenance of pregnancy in problem mares. Treatment should begin a minimum of 3 to 4 days prior to a show or event and must be continued daily in order to attain and maintain estrous suppression. ReguMare helps support the normal hormonal balance of your mare when temperament and marish behaviour adversely affects safe handling, willingness to work and performance. Simply apply the Regu-Mate solution at either the base of the mare's tongue or directly on her grain. WITHDRAWAL PERIOD. It can be given daily to a mare early in her season and usually within 3 days it will stop that oestrus. Suppression of estrus allows for a predictable occurrence of estrus following drug withdrawal. Regumate uses ORAL PROGESTIN SOLUTION 0.22% (2.2 mg/mL) FOR USE IN ANIMALS ONLY For suppression of estrus in mares. My mare has been on regumate since early February. “Regumate Equine 2.2 mg/ml oral solution for horses is indicated for mares to facilitate breeding. For owners or exhibitors of mares, you will be limited to the use of Regumate to control estrous. Right now not looking at marble. Positude helps address the behavioral side effects associated with the estrus cycle. Regu-Mate provides safe, effective suppression of estrus in mares - 95% effective after 3 days of treatment. This product is contraindicated for use in mares with a previous or current history of uterine inflammation. The cost-effective alternative to Regu-Mate®. Regumate 1 contains the drug altrenogest, a synthetic progestagen, and is labeled for use in mares to suppress estrus ("heat") display. My vet warned me this would leak but I came out the next morning to find over $250 worth of regumate leaked out of dosing gun overnight and hose was split. Detach syringe and administer solution orally at the rate of 1 mL per 110 pounds body weight (0.044 mg/kg) once daily for 15 consecutive days. 1000ml What is Regu-Mate Solution? Regu-Mate (altrenogest) Solution 0.22% is indicated to suppress estrus (period of the reproductive cycle when the mare ovulates and, if bred, is likely to conceive) in mares. Mares in winter anestrus with small follicles continued in anestrus and failed to exhibit normal estrus following withdrawal. The usual dose is 1 ml per 110 lbs body weight once daily for 15 consecutive days. Not to be administered by pregnant women. WARNING Regu-Mate® (altrenogest) Solution 0.22% is readily absorbed by the skin. Regu-Mate® is contraindicated for use in mares having a previous or current history of uterine inflammation. Avoid skin contact. Regumate is designed to prevent a mare from cycling, but Positude is not. Suppression of estrus allows for a predictable occurrence of estrus following drug withdrawal. Who is Regu-Mate Solution for? The classic method is daily oral administration of the progestin altrenogest (e.g., Regu-Mate). We just started my mare on 3 ml of im altrenogest that she gets once a week for four weeks and then possibly reduced down to every three weeks - I THINK this is the p+, but I'm wondering how such a low dose works and how it is different from the p4 ( which I know nothing about) and the boirelease. Detach syringe and administer solution orally at the rate of 1 mL per 110 pounds body weight (0.044 mg/kg) once daily for 15 consecutive days. Avoid skin contact. Regumate (altrenogest) appears to be the safest way to go when seeking to prevent a mare from coming into heat, says Beckman, although it does have a downside--it is expensive. Most people find that Positude is so effective in addressing their mare’s behavior that they do not need Regumate, but it is ok to use both. This facilitates the attainment of regular cyclicity during the transition from winter anestrus to the physiological breeding season. It is also commonly used to help maintain pregnancy in mares determined to be at risk of pregnancy loss. Suppression of estrus may be used to facilitate scheduled breeding during the physiological breeding season. Other altrenogest products are also marketed, however "Regumate" tends to be used as the catch-all name as a result of being the … Option #1: Daily oral administration of altrenogest (a synthetic progesterone) in oil. REGU-MATE (altrenogest) Solution 0.22% is indicated to suppress estrus in mares. Suppression of estrus allows for a predictable occurrence of estrus following drug withdrawal. Had to go buy new prescription and will never use gun again. Yes. Would love to hear from someone in the know. Remove cover from bottle dispensing tip and connect luer lock syringe (without needle). If the owner does not want to give the oral altrenogest daily, there are injectable altrenogest products that are compounded. Further, it is considering also prohibiting the use of a stronger progestin, Altrenogest or Regumate, in all geldings and stallions. The Science of Trusted Regu-Mate ® (altrenogest) From the Breeding Shed to the Show Ring Direct contact with the skin should be avoided. Use to schedule estrus in mares and breeding in mares to maximize breeding efficiency. (Xrays of stifle, hock, fetlock, etc all clean) So we decided to see if it was a cycle related issue and try regumate. 1ml Regumate Equine per 50 kg bodyweight per day for 10 consecutive days. The Dial-A-Dose system (2mL to 15mL) allows for an easy setting of dosage and accuracy of dosage. I wouldn't want to use Regumate without this device-nobody needs extra exposure to these kinds of hormones. Regumate Equine is used to control oestrus ("heat") in mares. The active ingredient is altrenogest 2.2 mg/ml. Regu-Mate is a solution for oral use only and is available in a 1,000 ml bottle. One is designed to last 7- 10 days and the other is a 30 day treatment. Meat and offal: 15 days. Altrenogest. Replace cover on bottle dispensing tip to prevent leakage. Protective gloves should be worn when handling product; women who are pregnant or suspect they are pregnant should not handle Regu-Mate Solution 0.22%. Regu-Mate requires a prescription from your veterinarian. Intervet Inc. d/b/a Merck Animal Health, Madison, NJ 07901, Better mare management: How to manage broodmares and performance mares more efficiently, When everything is at stake, trust Regu-Mate, Unwanted Horse Veterinary Relief Campaign (UHVRC), American Association of Equine Practitioners (AAEP), American Association of Equine Veterinary Technicians and Assistants (AAEVT), American College of Veterinary Internal Medicine (ACVIM), Northeast Association of Equine Practitioners (NEAEP), Texas Equine Veterinary Association (TEVA), United States Eventing Association (USEA), The only FDA-approved altrenogest with more than 20 million doses sold, Delivers safe, predictable control over a mare's reproductive cycle and reduces undesirable mood and behavioral changes, 15-day treatment regimen lets performance mares compete at their best, Strategic use helps accommodate mare's performance schedule, Easy to administer with Regu-Mate dosing device. Regumate fans often say it makes the mare feel “content” — their reasoning being that pregnant mares feel “content.” We believe a pregnant mare more likely feels like a pregnant woman — so if your mare could talk, she would probably tell you she feels bloated, fat, sluggish, fatigued and sleepy.

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